Key result
Neck pressure steps revealed that human vagal-cardiac responses are determined by net baroreceptor stimulation, whereas sympathetic muscle responses depend on the direction of pressure changes.
Why the study?
Does baroreflex modulation differentially affect human vagal-cardiac and sympathetic muscle activity in healthy volunteers?
Population
Healthy volunteers
Comparison
Positive and negative R-wave-triggered neck… vs Ambient pressure levels / baseline
Design
Other
Authors
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Does not support changes to clinical baroreflex assessment; extends models of differential vagal-sympathetic control in healthy humans.
Does baroreflex modulation differentially affect human vagal-cardiac and sympathetic muscle activity in healthy volunteers?
This physiological study demonstrates that vagal-cardiac responses depend on net baroreceptor stimulation, while sympathetic responses depend on the direction of pressure changes.
Fritsch et al. (1991) studied Healthy. Positive and negative R-wave-triggered neck pressure steps vs. Baseline/ambient levels was evaluated on R-R interval and peroneal nerve responses (vagal-cardiac and sympathetic muscle activity). Neck pressure steps revealed that human vagal-cardiac responses are determined by net baroreceptor stimulation, whereas sympathetic muscle responses depend on the direction of pressure changes.
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