Key result
Varicella-zoster virus infection triggers an aggressive immune reaction with serious complications in young healthy adults compared to a mild infection in children.
Why the study?
How does the immune response to Varicella-zoster virus differ between young adults and children?
How does the immune response to Varicella-zoster virus differ between young adults and children?
This overview highlights that Varicella-zoster virus infection causes a more aggressive and potentially fatal immune response in young adults compared to the typically mild infection seen in children.
Answers are grounded in this paper and cite their sources.
Supports heightened vigilance for VZV complications in young adults; leaves open mechanisms and management pending prospective studies.
The immune system is a defense system, both children, and adult have the same reaction toward pathogen, uses multiple defense mechanisms evolved to recognize and neutralize pathogens also have the ability to distinguish self from non-self cells, but in case of Varicella-zoster virus (VZV) that cause chicken pox, the immune system reacts differently in young healthy adult usually have an aggressive reaction serious complications can lead to death, compare with children infection is usually mild. This overview illustrates the chickenpox and difference of immune response between the children and young adult toward infection with the varicella-zoster virus.
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Alaa A Elnour (2018) conducted a review in Varicella-zoster virus (VZV) infection. Varicella-zoster virus (VZV) infection in young adults vs. Varicella-zoster virus (VZV) infection in children was evaluated on Immune response and complications. Varicella-zoster virus infection triggers an aggressive immune reaction with serious complications in young healthy adults compared to a mild infection in children.
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