Key result
Varicella-zoster virus infection in young adults triggers an aggressive immune reaction with serious complications compared to a typically mild response in children.
This overview highlights that VZV infection causes a more aggressive immune response and serious complications in young adults compared to children.
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May warrant heightened surveillance for complications in young adults with VZV; leaves open mechanistic and preventive questions for prospective study.
The immune system is a defense system, both children, and adult have the same reaction toward pathogen, uses multiple defense mechanisms evolved to recognize and neutralize pathogens also have the ability to distinguish self from non-self cells, but in case of Varicella-zoster virus (VZV) that cause chicken pox, the immune system reacts differently in young healthy adult usually have an aggressive reaction serious complications can lead to death, compare with children infection is usually mild. This overview illustrates the chickenpox and difference of immune response between the children and young adult toward infection with the varicella-zoster virus.
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Alaa A Elnour (2018) conducted a review in Varicella-zoster virus (VZV) infection. Varicella-zoster virus (VZV) infection in young adults vs. Varicella-zoster virus (VZV) infection in children was evaluated. Varicella-zoster virus infection in young adults triggers an aggressive immune reaction with serious complications compared to a typically mild response in children.
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