TypeⅡ heparin-induced thrombocytopenia presenting with acute arterial occlusion of the lower extremity in a patient on hemodialysis for 17 years

Shogo Kimura; Yuka Soga; Takeshi Ohsuga; Yu Tateiwa; Kazuki Yamanaka; Naohisa Handa; Toshiyuki Tsubouchi; Hidetoshi Tamaki; Fumihiko Kamiya; Koji Suzuki; Keiji Sano; Masahiko Koda; Hiroyuki Iwata; Norio Yasuda; Hisato Takatsu

doi:10.4009/jsdt.48.137

January 1, 2015Nihon Toseki Igakkai ZasshiOpen Access

TypeⅡ heparin-induced thrombocytopenia presenting with acute arterial occlusion of the lower extremity in a patient on hemodialysis for 17 years

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Key Points

To report a rare case of type II heparin-induced thrombocytopenia presenting with acute peripheral arterial occlusion after 17 years of maintenance hemodialysis.
Clinical case evaluation and literature review of a 71-year-old female on hemodialysis presenting with acute left toe necrosis.
Diagnostic assessment using contrast-enhanced computed tomography, Doppler ultrasonography, serial platelet monitoring, and anti-heparin/PF4 antibody assays.
Platelet counts fell acutely from 189,000/μL to 49,000/μL alongside strongly positive HIT antibodies and digital artery occlusion.
Discontinuation of heparin and continuous anticoagulation with argatroban enabled platelet recovery and sustained hemodialysis until discharge on day 70, following lower extremity amputation on day 4.

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Implication

Case report shows acute arterial occlusion from type II heparin-induced thrombocytopenia in a 17-year hemodialysis patient, highlighting maintenance risks.

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Kimura et al. (2015) studied this question.

synapsesocial.com/papers/6a9b073d3f5340f39dd15d55 https://doi.org/10.4009/jsdt.48.137

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TypeⅡ heparin-induced thrombocytopenia presenting with acute arterial occlusion of the lower extremity in a patient on hemodialysis for 17 years

Key Points

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Implication

Abstract

Discussion

Cite This Study

TypeⅡ heparin-induced thrombocytopenia presenting with acute arterial occlusion of the lower extremity in a patient on hemodialysis for 17 years

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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