Key result
Mitral valve repair for active endocarditis was associated with lower hospital mortality (11.6% vs 29.7%, P=0.006) and higher 15-year overall survival (57% vs 36%, P=0.03) compared to replacement.
Why the study?
Does mitral valve repair improve survival and reduce reoperation compared to mitral valve replacement in patients with active native mitral valve endocarditis?
Population
192 consecutive patients undergoing mitral valve surgery for active native mitral valve endocarditis at a…
Comparison
Mitral valve repair (n=155) vs Mitral valve replacement (n=37)
Design
Cohort
Follow-up
median 122 months (repair) and 146 months (replacement)
Authors
Loading...
Supports repair when feasible in active native mitral endocarditis; leaves open need for randomized confirmation of survival benefit.
Cohort (n=192)
No
Does mitral valve repair improve survival and reduce reoperation compared to mitral valve replacement in patients with active native mitral valve endocarditis?
Absolute Event Rate: 57% vs 36%
p-value: p=0.03
An early, repair-oriented surgical approach for active mitral valve endocarditis yields high reparability rates, good long-term durability, and low recurrence rates.
Solari et al. (2018) conducted a cohort in active infective mitral valve endocarditis (n=192). Mitral valve repair vs. Mitral valve replacement was evaluated on 15-year overall survival (p=0.03). Mitral valve repair for active endocarditis was associated with lower hospital mortality (11.6% vs 29.7%, P=0.006) and higher 15-year overall survival (57% vs 36%, P=0.03) compared to replacement.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: