Key result
Perianastomotic tissue oxygen tension above 55 mmHg was associated with a 10% leakage rate compared to 100% when tension was less than 25 mmHg (P<0.001).
Why the study?
Does suture technique and perianastomotic tissue oxygen tension affect colonic anastomotic healing in a rabbit model?
Does suture technique and perianastomotic tissue oxygen tension affect colonic anastomotic healing in a rabbit model?
Absolute Event Rate: 10% vs 100%
p-value: p=<0.001
Perianastomotic tissue oxygen tension strongly predicts colonic anastomotic healing and leakage rate in a rabbit model.
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Tissue oxygen tension may predict anastomotic healing in rabbit models; leaves open translation to human colorectal surgery.
Shandall et al. (1985) studied Colonic anastomoses. Perianastomotic tissue oxygen tension (T02) > 55 mmHg vs. T02 < 25 mmHg was evaluated on Leakage rate (p=<0.001). Perianastomotic tissue oxygen tension above 55 mmHg was associated with a 10% leakage rate compared to 100% when tension was less than 25 mmHg (P<0.001).
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