Key result
Protein-based biomarkers and circulating microRNAs show potential as molecular biomarkers to predict the course of bicuspid aortic valve-associated aortopathy.
Population
Patients with bicuspid aortic valve (BAV) disease and bicuspid aortopathy
Design
Review
Authors
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May aid risk stratification in BAV aortopathy; leaves open need for prospective validation before clinical adoption.
Circulating biomarkers, including microRNAs and proteins, hold promise for improving risk stratification and predicting the course of bicuspid aortopathy beyond current clinical phenotypes.
Girdauskas et al. (2018) conducted a review in Bicuspid aortic valve (BAV) disease and aortopathy. Circulating biomarkers (protein-based and non-coding RNAs) was evaluated. Protein-based biomarkers and circulating microRNAs show potential as molecular biomarkers to predict the course of bicuspid aortic valve-associated aortopathy.
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