Key result
No significant relationship was observed between the presence of atherosclerotic plaque and the amount or density of mediastinal fat, though sternal fat thickness was significantly greater in patients without plaques.
Why the study?
It was unclear whether mediastinal adipose tissue plays a role in thoracic aortic atherosclerosis, including the relationship of its amount and density with age, sex, and aortic atherosclerotic plaque.
Cross-Sectional (n=45)
No
Sternal fat thickness and aortic diameter, but not mediastinal fat amount or density, are associated with the presence of thoracic aortic atherosclerotic plaques on CT imaging.
No mediastinal fat-plaque link seen on CT; hypothesis-generating and needs prospective validation before clinical consideration.
Aim: We aimed to investigate whether the mediastinal adipose tissue plays a role in thoracic aortic atherosclerosis with thoracic Computed Tomography (CT) imaging. We aimed to elucidate the relationship between the amount and density of mediastinal adipose tissue, age, sex, and the presence of atherosclerotic plaque in the aorta. Material and Method: In this retrospective study, the thoracic computed tomography (CT) images of 45 patients (21 men and 24 women) were examined in two groups. There were 23 patients aged >60 years in group 1 and 22 patients aged 60 years (group 1) and
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Sarıkaya et al. (2023) conducted a cross-sectional in Thoracic aortic atherosclerosis (n=45). Mediastinal adipose tissue and sternal fat thickness vs. Patients without atherosclerotic plaques was evaluated on Presence of atherosclerotic plaque in the aorta and its association with mediastinal fat amount, fat density, and sternal fat thickness (p=0.483). No significant relationship was observed between the presence of atherosclerotic plaque and the amount or density of mediastinal fat, though sternal fat thickness was significantly greater in patients without plaques.
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