Key result
Patients admitted with heart failure in 2016 had fewer symptoms or diuretic requirements compared to 2002 (63% vs 98.6%, p<0.001), alongside increased HFpEF prevalence and improved HFrEF medication rates.
Why the study?
The study aimed to investigate differences in characteristics of patients admitted with heart failure to Tomsk National Research Medical Center in 2002 compared with 2016.
Observational (n=588)
No
Answers are grounded in this paper and cite their sources.
Prescription rates for prognostic medications in HFrEF improved significantly between 2002 and 2016, though a substantial increase in asymptomatic HFpEF diagnoses raises questions about diagnostic appropriateness.
AIM: To investigate the difference in characteristics of patients admitted to the Tomsk National Research Medical Center with a diagnosis of heart failure (HF) in 2002 and 2016. METHODS: Medical charts of all patients hospitalised in a single centre, with a diagnosis of HF, were included. Two three‑month periods were compared from January 2002 (n=210) and January 2016 (n=378). RESULTS: Fewer patients with HF had symptoms or required diuretics in 2016 (63 % vs 98,6 %, p<0.001). During this period the percentage of patients with HFpEF increased from 58.6 % to 74.1 % (p=0.001) whereas those with HFrEF remained similar (19.5 % vs 14.0 %, p=0.1) and those with HFmrEF declined (21.9 % vs 11,9 %, p=0.007). In patients with HFrEF the prescription of ACEi / ARB remained similar (80.4 vs 88 %, p=0.3), beta‑blockers increased from 68 to 85 % (p=0.03) and aldosterone antagonists from 9.7 to 49 % (p<0.001). CONCLUSION: Prescription rates for prognostic medications in HFrEF improved in 2016. The substantial percentage of patients diagnosed with HFpEF without symptoms or diuretic raises the question of whether a diagnosis of HF was appropriate in some cases.
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Гарганеева et al. (2018) conducted an observational in Heart failure (n=588). Admission in 2016 vs. Admission in 2002 was evaluated on Symptoms or requirement for diuretics (p=<0.001). Patients admitted with heart failure in 2016 had fewer symptoms or diuretic requirements compared to 2002 (63% vs 98.6%, p<0.001), alongside increased HFpEF prevalence and improved HFrEF medication rates.
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