Key result
Androgenetic alopecia was not significantly associated with metabolic syndrome compared to controls (8.08% vs. 7.69%, p=0.742), but was linked to dyslipidemia and elevated systolic blood pressure.
Why the study?
Androgenetic alopecia has been linked to cardiovascular diseases and metabolic syndrome, but studies on these relationships among Nigerians are rare.
Is androgenetic alopecia associated with cardiovascular risk factors and metabolic syndrome in Nigerian adults?
Cross-Sectional (n=520)
Is androgenetic alopecia associated with cardiovascular risk factors and metabolic syndrome in Nigerian adults?
In Nigerian adults, androgenetic alopecia is associated with cardiovascular risk factors such as dyslipidemia and elevated systolic blood pressure, though not with a significantly higher prevalence of metabolic syndrome.
Background: Androgenetic alopecia (AGA) has been linked to cardiovascular diseases (CVDs) and metabolic syndrome (MetS). Works on AGA, cardiovascular risk factors (CVRFs) and MetS are rare among Nigerians. Aim: This study set out to determine the relationship among CVRFs, MetS, and AGA. Subjects and Methods: This is a cross-sectional study done among adults who were 18 years and above in selected communities in Ogbomoso on 260 consenting AGA participants as well as 260 age controls without AGA. They were matched for age and sex using a multistage sampling method. Anthropometric measurements, fasting blood glucose, and lipid profile samples were collected. MetS was diagnosed using International Diabetes Federation criteria. Data were analyzed using IBM SPSS version 20. Ethical approval was gotten before commencement of the study (LTH/OGB/EC/2017/162). Result: Metabolic syndrome in AGA was higher than in controls (8.08% vs. 7.69%, p = 0.742). AGA was significantly associated with elevated mean systolic blood pressure (SBP) (p = 0.008), low High Density Lipoprotein (HDL-c) (p < 0.001), alcohol intake (p < 0.001), dyslipidaemia (p = 0.002), and sedentary lifestyle (p = 0.010). The correlates of AGA severity in male and female gender are age (p < 0.001 and 0.009 respectively), SBP (p = 0.024) and abdominal obesity (p = 0.027) in male gender. Conclusion: AGA in Nigerians is associated with dyslipidaemia, alcohol intake, and sedentary lifestyle. AGA severity is related to age, higher mean SBP, abdominal obesity and low HDL-c in male and age, and Body mass index in females. Nigerians with AGA should be screened for dyslipidaemia and counseled against the use of alcohol and sedentary lifestyle.
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Oiwoh et al. (2023) conducted a cross-sectional in Androgenetic alopecia (n=520). Androgenetic alopecia vs. Controls without androgenetic alopecia was evaluated on Metabolic syndrome (p=0.742). Androgenetic alopecia was not significantly associated with metabolic syndrome compared to controls (8.08% vs. 7.69%, p=0.742), but was linked to dyslipidemia and elevated systolic blood pressure.
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