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January 1, 1980Orthopedics & TraumatologyOpen Access

Anesthetic Management of Total Hip Replacement with Methylmethacrylate Bone Cement

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Key result

Epidural anesthesia was associated with less blood loss and a slighter hypotensive response to methylmethacrylate bone cement insertion during total hip replacement compared to general anesthesia.

Why the study?

Does epidural anesthesia reduce hypotensive responses and blood loss compared to general anesthesia in patients undergoing total hip replacement with bone cement?

Population

54 patients undergoing total hip replacement with methylmethacrylate bone cement.

Comparison

Epidural anesthesia vs General anesthesia (GOF or NLA)

Design

Cohort

Follow-up

Intraoperative

Authors

KSKenichi SakanashiNUNaoyuki UedaHWHiroshi Watanabe

Discussion

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Overview

May favor epidural anesthesia in cemented hip replacement to limit blood loss and hypotension; leaves open need for randomized trials before practice change.

Study Design

Type

Observational (n=54)

Multicenter

No

Structured PICO

Does epidural anesthesia reduce hypotensive responses and blood loss compared to general anesthesia in patients undergoing total hip replacement with bone cement?

P
Population
54 patients (mean age 53.6 years) undergoing total hip replacement with methylmethacrylate bone cement, analyzed for intraoperative cardiovascular changes.
E
Exposure
Epidural anesthesia
C
Comparator
General anesthesia (GOF or NLA)
O
Outcome
Cardiovascular effects (blood pressure changes) upon bone cement insertionsafety

Epidural anesthesia may be preferable to general anesthesia for total hip replacement with bone cement due to reduced intraoperative blood loss and blunted hypotensive responses.

Limitations

  • Small sample size
  • Observational study design without randomization
  • Potential confounding by patient baseline characteristics

Cite This Study

Sakanashi et al. (1980) conducted an observational in Total hip replacement (n=54). Epidural anesthesia vs. General anesthesia was evaluated on Hypotensive response to bone cement insertion. Epidural anesthesia was associated with less blood loss and a slighter hypotensive response to methylmethacrylate bone cement insertion during total hip replacement compared to general anesthesia.

synapsesocial.com/papers/6a9bd0ec0b073dbbe4b20da3https://doi.org/10.5035/nishiseisai.29.583
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Hemodynamic changes in patients undergoing cemented total hip replacement surgery: a literature review2020 · 3 citations
  2. 2Cardiovascular effects of total hip placement in man; With observations on the effects of methyl methacrylate on the isolated rabbit heart1977 · 27 citations
  3. 3The effect of anaesthesia on changes in blood pressure and plasma cortisol levels induced by cementation with methylmethacrylate1986 · 25 citations
  4. 4Effect of hypotensive epidural anaesthesia on acetabular cement-bone fixation in total hip arthroplasty1991 · 37 citations
  5. 5Cardiovascular Effects of Implanted Acrylic Bone Cement1971 · 132 citations