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September 5, 2026EP EuropaceOpen Access

LAAC is associated with varying rates of bleeding, procedural safety events, and mortality.

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Key result

Left atrial appendage closure is associated with varying rates of bleeding-related conditions, procedural safety events, and mortality.

Authors

GMGrégoire MassoulliéCFCome FleuryETEmeline Tourret

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Overview

Baseline bleeding conditions warrant caution in LAA closure candidates; leaves open whether mitigation alters mortality.

Key Points

  • Evaluate the association between baseline bleeding-related conditions, procedural complications, and long-term mortality in patients undergoing left atrial appendage closure.
  • Analyzed clinical safety outcomes, procedural success, and post-intervention adverse events in patients treated with left atrial appendage closure.
  • Assessed the prognostic impact of pre-existing bleeding conditions on subsequent mortality and vascular complications.
  • Procedural safety profiles demonstrate feasibility, though baseline bleeding vulnerability influences perioperative risk.
  • Pre-existing bleeding-related conditions are linked to variations in post-procedural adverse events and long-term overall mortality.

Cite This Study

Massoullié et al. (2026) studied this question. Left atrial appendage closure is associated with varying rates of bleeding-related conditions, procedural safety events, and mortality.

synapsesocial.com/papers/6a9bd4126b95aff0620eb790https://doi.org/10.1093/europace/euag235
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