Haemodynamic performance of a new pericardial aortic bioprosthesis during exercise and recovery: comparison with pulmonary autograft, stentless aortic bioprosthesis and healthy control groups
Key result
The Trifecta aortic valve bioprosthesis demonstrated inferior haemodynamics during exercise compared to the Ross operation and healthy controls (P<0.05), but showed a nearly physiological recovery.
Why the study?
Does the Trifecta pericardial aortic bioprosthesis improve haemodynamic performance during exercise and recovery compared to stentless aortic bioprostheses, the Ross operation, or healthy controls?
Population
146 individuals, comprising 32 patients with a Trifecta pericardial aortic bioprosthesis, 49 with a Ross…
Comparison
Trifecta pericardial aortic bioprosthesis (T-AVB) vs Ross operation, Medtronic freestyle stentless…
Design
Cohort
Follow-up
mean 5 ± 2 months (for T-AVB group)
Authors
Discussion
Loading...
Member takes
Implication
May inform valve selection in active patients; leaves open superiority to stentless valves pending randomized trials.
Study Design
Type
Observational (n=146)
Structured PICO
Does the Trifecta pericardial aortic bioprosthesis improve haemodynamic performance during exercise and recovery compared to stentless aortic bioprostheses, the Ross operation, or healthy controls?
P
Population
146 participants including patients with a Trifecta aortic valve bioprosthesis, Ross operation, Medtronic freestyle bioprosthesis, and healthy controls evaluated for haemodynamics during exercise and recovery.
E
Exposure
Trifecta pericardial aortic bioprosthesis (T-AVB)
C
Comparator
Ross operation (RO), Medtronic freestyle stentless aortic bioprosthesis (MF-AVB), and healthy controls
O
Outcome
Haemodynamic performance (mean outflow tract gradient, effective orifice area index, and valvular resistance) at rest, during supine exercise stress testing, and during a 10-min recovery periodsurrogate
Main Result
p-value: p=<0.05
The Trifecta pericardial aortic bioprosthesis demonstrates promising exercise haemodynamics and physiological recovery patterns that are superior to stentless bioprostheses, though still inferior to the Ross operation and healthy native valves.
Cite This Study
Hanke et al. (2013) conducted an observational in Aortic valve replacement (n=146). Trifecta aortic valve bioprosthesis vs. Ross operation, Medtronic freestyle bioprosthesis, and healthy controls was evaluated on Haemodynamic performance (mean outflow tract gradient, effective orifice area index, and valvular resistance) during exercise and recovery (p=<0.05). The Trifecta aortic valve bioprosthesis demonstrated inferior haemodynamics during exercise compared to the Ross operation and healthy controls (P<0.05), but showed a nearly physiological recovery.