Key result
Polyvascular disease was independently associated with a significantly higher risk of 1-year all-cause death (HR 2.21) compared to acute myocardial infarction alone.
Why the study?
The impact of polyvascular disease in patients with acute myocardial infarction in the contemporary percutaneous coronary intervention era required investigation.
Does the presence of polyvascular disease increase the risk of all-cause death, MACE, and major bleeding in patients with acute myocardial infarction in the contemporary era of percutaneous coronary intervention?
Population
3,411 patients with AMI enrolled in the JAMIR registry
Comparison
1-bed (AMI only) vs 2-bed vs 3-bed polyvascular disease groups
Design
Multicenter prospective registry post hoc subanalysis
Authors
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May inform post-AMI risk stratification; leaves open whether targeted interventions improve outcomes.
Observational (n=3,411)
Yes
Does the presence of polyvascular disease increase the risk of all-cause death, MACE, and major bleeding in patients with acute myocardial infarction in the contemporary era of percutaneous coronary intervention?
Hazard Ratio: 2.21 (95% CI 1.48–3.29)
p-value: p=<0.001
In patients with acute myocardial infarction undergoing contemporary PCI, the presence of polyvascular disease is independently associated with a significantly higher risk of 1-year all-cause mortality, MACE, and major bleeding.
Arai et al. (2023) conducted an observational in Acute Myocardial Infarction (n=3,411). Polyvascular disease vs. Acute myocardial infarction only (1 vascular bed) was evaluated on All-cause death within 1 year (HR 2.21, 95% CI 1.48-3.29, p=<0.001). Polyvascular disease was independently associated with a significantly higher risk of 1-year all-cause death (HR 2.21) compared to acute myocardial infarction alone.
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