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November 1, 1976Journal of Applied Physiology

Blood flow in branching vessels

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Key result

Arterial-type flows in a branching tube model produced previously unreported vortex sinks downstream of the branching port, creating stagnation regions potentially related to atheroma and thrombus formation.

Population

Water-Plexiglas tube model simulating flow conditions commonly encountered in major vessels

Design

Preclinical

Authors

APAlfred C. PinchakMetroHealthSOS. OstrachCase Western Reserve University

Discussion

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Implication

Stagnation at arterial branches may promote atheroma; leaves open clinical relevance pending in vivo studies.

Structured PICO

P
Population
Water-Plexiglas tube model simulating flow conditions commonly encountered in major vessels
E
Exposure
Flow visualization studies
O
Outcome
Secondary flow patterns in the main line downstream of a branching vessel

In vitro flow visualization demonstrates complex secondary flow patterns and stagnation points at arterial branches, which may contribute to atheroma and thrombus formation.

Cite This Study

Pinchak et al. (1976) studied Simulated flow conditions in major vessels. Water-Plexiglas tube model was evaluated on Secondary flow patterns and vortex sinks. Arterial-type flows in a branching tube model produced previously unreported vortex sinks downstream of the branching port, creating stagnation regions potentially related to atheroma and thrombus formation.

synapsesocial.com/papers/6a9bfc108239e631fdcc63b1https://doi.org/10.1152/jappl.1976.41.5.646
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Particle flow behavior in models of branching vessels1985 · 100 citations
  2. 2Particle flow behaviour in models of branching vessels: I. Vortices in 90° T-junctions1979 · 107 citations
  3. 3Unsteady flow in a branch1976 · 35 citations
  4. 4Blood Flow Dynamics with Special Reference to Atherogenesis1984
  5. 5A Comparison of Steady and Pulsatile Flow in Symmetrically Branched Tubes1982 · 10 citations