Key result
Routine use of thrombus aspiration in primary percutaneous coronary intervention has yielded disappointing results in recent large-scale trials, leading to its decreased use.
Discusses the evolving perspective on thrombus aspiration during primary PCI, highlighting its decline in routine use following disappointing results from recent large-scale trials.
Thrombus aspiration during primary percutaneous coronary intervention (pPCI) has been used to improve myocardial perfusion through a reduction of the thrombotic burden eventually resulting into better clinical outcomes (1,2). After the initial enthusiasm derived from the mortality reduction shown in early randomized and observational studies (3-7), disappointing results have been yielded in more recent larger scale trials testing the routine use of thrombus aspiration in pPCI (8-12). As a consequence, this technique has lost its initial appeal such that it is currently often neglected or even considered as a useless hassle by the interventional cardiologists.
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Mangiacapra et al. (2017) conducted an editorial in Primary percutaneous coronary intervention. Thrombus aspiration was evaluated. Routine use of thrombus aspiration in primary percutaneous coronary intervention has yielded disappointing results in recent large-scale trials, leading to its decreased use.
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