Key result
Among patients with panic attacks, 50% had mitral valve prolapse and 26% of women had thyroid abnormalities, suggesting an association between these conditions.
Cross-Sectional (n=65)
In patients with panic attacks, there is a high prevalence of mitral valve prolapse and autoimmune thyroid disorders, though they do not appear directly related to each other.
Should not change screening practices in panic disorder; leaves open causal links requiring prospective studies.
Panic disorder has been associated with mitral valve prolapse and thyroid abnormalities. Mitral valve prolapse has also been associated with thyroid abnormalities. The authors studied a consecutive series of 65 patients self-referred for evaluation of panic attacks, who were examined for cardiac and thyroid abnormalities. Fifty percent of the patients had mitral valve prolapse according to both cardiac auscultation and echocardiography. Twenty-six percent of the women had some thyroid abnormality; 17% had thyroid microsomal antibodies. There was no apparent relationship between mitral valve prolapse and thyroid abnormalities. These observations suggest that panic attacks, mitral valve prolapse, and autoimmune thyroid disorders are associated.
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Matuzas et al. (1987) conducted a cross-sectional in Panic attacks (n=65). Panic attacks was evaluated on Prevalence of mitral valve prolapse and thyroid abnormalities. Among patients with panic attacks, 50% had mitral valve prolapse and 26% of women had thyroid abnormalities, suggesting an association between these conditions.
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