Key result
Serum myoglobin levels measured by radioimmunoassay were markedly elevated in all 32 patients with myocardial infarction (mean 1368 ng/ml) compared to normal individuals (mean 25 ng/ml).
Why the study?
Does serum myoglobin measured by radioimmunoassay differentiate patients with acute myocardial infarction from normal individuals and patients with other causes of chest pain?
Observational (n=81)
Does serum myoglobin measured by radioimmunoassay differentiate patients with acute myocardial infarction from normal individuals and patients with other causes of chest pain?
Serum myoglobin measured by radioimmunoassay is markedly elevated in patients with acute myocardial infarction within 12 hours of symptom onset, suggesting its utility as an early biomarker for myocardial necrosis.
No takes yet. Share an insight, caveat, or question.
Serum myoglobin may support early MI detection; leaves open diagnostic specificity versus other chest pain causes in prospective studies.
Reichlin et al. (1978) conducted an observational in Coronary heart disease (n=81). Radioimmunoassay for human myoglobin vs. Normal individuals was evaluated on Serum myoglobin level. Serum myoglobin levels measured by radioimmunoassay were markedly elevated in all 32 patients with myocardial infarction (mean 1368 ng/ml) compared to normal individuals (mean 25 ng/ml).
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: