Key result
Serum myoglobin identifies acute myocardial infarction with ~91% sensitivity, often rising before CK-MB.
Why the study?
The performance characteristics of serum myoglobin determinations in the diagnosis of acute myocardial infarction were not well defined.
Observational (n=118)
Absolute Event Rate: 91% vs 94%
No takes yet. Share an insight, caveat, or question.
May support early MI detection in CCU; leaves open validation against modern troponin assays.
Oxley et al. (1979) conducted an observational in acute myocardial infarction (MI) (n=118). Serum myoglobin determination vs. CK-MB was evaluated on Diagnostic sensitivity for acute myocardial infarction. Serum myoglobin determination demonstrated 91% sensitivity and 85% specificity for diagnosing acute myocardial infarction, with elevation preceding CK-MB in 38% of cases.
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