Why the study?
Does treatment of thyroid disorders improve myocardial collagen content assessed by ultrasonic tissue characterization in patients with thyroid disorders?
Population
30 subjects: 8 hyperthyroid patients, 10 hypothyroid patients, 2 patients with thyroid hormone resistance…
Comparison
Treatment for thyroid disorders vs Baseline (before treatment) and euthyroid controls
Design
Cohort
Follow-up
120 days
Authors
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Thyroid replacement may normalize myocardial fibrosis markers in hypothyroidism; hypothesis-generating and should not yet change practice.
Does treatment of thyroid disorders improve myocardial collagen content assessed by ultrasonic tissue characterization in patients with thyroid disorders?
Treatment of hypothyroidism normalizes myocardial collagen content as assessed by ultrasonic tissue characterization, suggesting thyroid hormones inhibit myocardial collagen synthesis.
Ciulla et al. (2001) studied this question.
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