Key result
Hyperthyroidism linked to augmented myocardial relaxation that normalizes after antithyroid treatment.
Why the study?
Does hyperthyroidism affect left ventricular myocardial relaxation in patients without cardiac disease?
Population
80 subjects, comprising 31 hyperthyroid (HTH) patients without cardiac disease and 49 normal controls (NC).
Comparison
Hyperthyroidism vs Normal controls
Design
Cross-sectional
Authors
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Hyperthyroidism may augment LV relaxation in patients without heart disease; leaves open whether this affects outcomes or management.
Observational (n=80)
Does hyperthyroidism affect left ventricular myocardial relaxation in patients without cardiac disease?
Hyperthyroidism augments left ventricular myocardial relaxation, an effect that correlates with thyroid hormone levels and is reversible with antithyroid treatment.
Dazai et al. (1992) conducted an observational in Hyperthyroidism (n=80). Hyperthyroidism (elevated thyroid hormone) vs. Normal controls was evaluated on Left ventricular diastolic indices (IIa-MVO, maxPWDR, peak E, peak A). Hyperthyroidism in 31 patients was associated with augmented myocardial relaxation compared to 49 normal controls, which normalized in 14 patients after antithyroid treatment.
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