Key result
Elevated serum concentrations of type III procollagen, 7S collagen, or troponin T were associated with a significantly poorer short-term prognosis in patients with cardiomyopathy (p < 0.001).
Why the study?
Do elevated serum levels of type III procollagen, 7S collagen, and troponin T predict poor short-term prognosis in patients with idiopathic dilated or secondary cardiomyopathy?
Cohort (n=21)
Do elevated serum levels of type III procollagen, 7S collagen, and troponin T predict poor short-term prognosis in patients with idiopathic dilated or secondary cardiomyopathy?
p-value: p=< 0.001
Elevated serum collagen markers and troponin T may serve as useful prognostic indicators for poor short-term outcomes in patients with cardiomyopathy.
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May aid short-term risk stratification in cardiomyopathy; hypothesis-generating and requires prospective validation before clinical use.
Sato et al. (1997) conducted a cohort in Idiopathic dilated cardiomyopathy and secondary cardiomyopathy (n=21). Elevated serum concentrations of type III procollagen, 7S collagen, or cardiac troponin T vs. Normal serum concentrations was evaluated on Short term prognosis (p=< 0.001). Elevated serum concentrations of type III procollagen, 7S collagen, or troponin T were associated with a significantly poorer short-term prognosis in patients with cardiomyopathy (p < 0.001).
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