Key result
Intradermal fractional dose inactivated poliovirus vaccine is being evaluated against intramuscular full dose vaccine for immunogenicity and efficacy in a Cochrane Review protocol.
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Fractional-dose intradermal IPV not ready for clinical use; leaves open comparative immunogenicity and efficacy pending review.
This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: compare the immunogenicity and efficacy of a full inactivated poliovirus vaccine (IPV) initial immunization schedule using fractional dose IPV given via the intradermal route versus full dose IPV given via the intramuscular route.
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Jaiswal et al. (2015) studied this question. Intradermal fractional dose inactivated poliovirus vaccine is being evaluated against intramuscular full dose vaccine for immunogenicity and efficacy in a Cochrane Review protocol.
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