Key result
Redo surgery for prosthetic valve thrombosis was associated with lower mortality (13.33% vs 40%) and recurrence (0% vs 40%) compared to fibrinolytic therapy.
Why the study?
Does redo surgery reduce mortality and recurrence compared to fibrinolytic therapy in patients with prosthetic valve obstruction?
Population
30 patients with prosthetic valve thrombosis, diagnosis confirmed by transthoracic and transesophageal…
Comparison
Redo surgery vs Fibrinolytic therapy (thrombolysis)
Design
Cohort
Authors
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May support redo surgery consideration in prosthetic valve thrombosis; leaves open need for randomized confirmation before practice change.
Cohort (n=30)
Does redo surgery reduce mortality and recurrence compared to fibrinolytic therapy in patients with prosthetic valve obstruction?
Absolute Event Rate: 13.33% vs 40%
Redo surgery appears to offer lower mortality and recurrence rates compared to fibrinolysis for patients with prosthetic valve thrombosis, particularly in hemodynamically stable patients.
Shende et al. (2017) conducted a cohort in Prosthetic valve thrombosis (n=30). Surgery vs. Fibrinolytic therapy was evaluated on Mortality rate. Redo surgery for prosthetic valve thrombosis was associated with lower mortality (13.33% vs 40%) and recurrence (0% vs 40%) compared to fibrinolytic therapy.
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