Key result
Balloon mitral valvotomy during pregnancy significantly increased mitral valve area from 0.92 to 2.06 cm2 (p<0.0001) and was associated with safe pregnancy and neonatal outcomes.
Why the study?
Does Balloon Mitral Valvotomy (BMV) improve mitral valve area safely in pregnant women with severe mitral stenosis?
Cohort (n=84)
Does Balloon Mitral Valvotomy (BMV) improve mitral valve area safely in pregnant women with severe mitral stenosis?
Absolute Event Rate: 2.06% vs 0.92%
p-value: p=< 0.0001
Balloon mitral valvotomy during the second trimester of pregnancy is feasible, safe, and effectively increases mitral valve area with favorable neonatal outcomes.
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Supports BMV feasibility in pregnant severe MS; hypothesis-generating, needs randomized confirmation before practice change.
Pingali et al. (2015) conducted a cohort in Severe mitral stenosis in pregnancy (n=84). Balloon mitral valvotomy (BMV) was evaluated on Mitral valve area (cm2) (p=< 0.0001). Balloon mitral valvotomy during pregnancy significantly increased mitral valve area from 0.92 to 2.06 cm2 (p<0.0001) and was associated with safe pregnancy and neonatal outcomes.
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