Key result
Balloon mitral valvotomy during pregnancy significantly increased mitral valve area from 0.92 to 2.06 cm2 (p<0.0001) with no adverse pregnancy or neonatal outcomes.
Why the study?
Is Balloon Mitral Valvotomy (BMV) safe and effective during pregnancy for women with severe mitral stenosis?
Observational (n=84)
Is Balloon Mitral Valvotomy (BMV) safe and effective during pregnancy for women with severe mitral stenosis?
Absolute Event Rate: 2.06% vs 0.92%
p-value: p=< 0.0001
Balloon mitral valvotomy during the second trimester of pregnancy is a feasible and safe intervention for severe mitral stenosis, significantly improving valve area without adverse neonatal outcomes.
May support BMV for severe MS in pregnancy; leaves open need for randomized confirmation.
hazards of radiation, we retrospectively evaluated pregnancy and neonatal outcomes after BMV.Methods: During January 2002 to January 2015, eighty-four BMV interventions during pregnancy were observed.Data on pregnancy and neonatal outcome was evaluated.Results: Mean maternal age of all patients was 25.21 AE 7.66 years with maximum number of women in 18-25 years (67.86%)age group.Primigravida (36.90%) and second gravida (42.86%) were common.Mean gestational age at which BMV performed was 22.43 AE 5.70 weeks with majority of interventions during second trimester (84.52%).Significant increase in mitral valve area was observed after BMV (baseline: 0.92 AE 0.2 cm 2 ; post-BMV: 2.06 AE 0.3 cm 2 p < 0.0001).One-third (56/84) pregnancies had full-term birth (≥37 weeks of gestation), twenty-four (28.57.%) had preterm delivery, three patients had medical termination of pregnancy and one was macerated still birth.Birth weight of majority of newborn babies (76/81, 93.82%) was 2.5 kg and above with only five (6.17%) babies weighing below 2.5 kg.APGAR scores (mean AE SD) at 1 minute, 5 minute and 10 minute were 5.98 AE 0.68, 6.98 AE 0.72 and 8.23 AE 0.45.Discussion and conclusion: BMV during second trimester of pregnancy is feasible and safe.A good success rate was observed in our experience.No adverse outcomes were observed for pregnancy and in neonates.With experienced hands, BMV is the choice of intervention for severe mitral stenosis in pregnancy.
No takes yet. Share an insight, caveat, or question.
Suseno et al. (2015) conducted an observational in Severe mitral stenosis in pregnancy (n=84). Balloon Mitral Valvotomy (BMV) vs. Baseline (pre-BMV) was evaluated on Mitral valve area (p=< 0.0001). Balloon mitral valvotomy during pregnancy significantly increased mitral valve area from 0.92 to 2.06 cm2 (p<0.0001) with no adverse pregnancy or neonatal outcomes.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: