Key result
Children on chronic hemodialysis had a 60% prevalence of left ventricular hypertrophy, which was significantly higher than healthy controls, though it did not correlate significantly with blood pressure.
Why the study?
Does hypertension correlate with left ventricular hypertrophy in children on chronic hemodialysis?
Cross-Sectional (n=40)
No
Does hypertension correlate with left ventricular hypertrophy in children on chronic hemodialysis?
Absolute Event Rate: 60% vs 0%
p-value: p=<0.001
In children on chronic hemodialysis, left ventricular hypertrophy is highly prevalent but does not significantly correlate with blood pressure, suggesting other cardiovascular risk factors drive the increase in left ventricular mass.
May warrant LVH evaluation regardless of BP in pediatric hemodialysis; leaves open non-BP drivers and needs longitudinal confirmation.
Cardiovascular complications are the major cause of mortality and morbidity in children with end-stage renal disease who are treated with chronic hemodialysis Arterial hypertension is a major cardiovascular risk factors in this population. The aim is that children who are on HD displays the prevalence of hypertension, to check arterial pressure before and after HD and displays the correlation with the left ventricle mass (LVM). Method: The study in 20 patients on chronic HD and 20 healthy control group children, blood pressure was measured by sphygmomanometer before and after HD. Also echocardiography were measured left ventricular mass before and after HD and track the correlation of these two parameters. Results: The prevalence of hypertension in children on HD is 62% for significant different compared to the control group (p <0.001) .. TA values of systolic and diastolic significantly lower after HD. (P <0.05). After HD TA values were significantly higher than the value of TA (p <0.05) in healthy children. The prevalence of LVH was 60% in children on HD and statistically be statistically highe then to the control group (p <0.001). The correlation between LVH and increased TA was linear but was not statistically significant in either group of patients. In conclusion: The fact that hypertension does not correlate significantly with left ventricular mass suggests that the increase in LVM except high blood pressure and affect other cardiovascular risk factors.
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Lj. Šulović (2014) conducted a cross-sectional in End-stage renal disease on chronic hemodialysis (n=40). Chronic hemodialysis vs. Healthy children was evaluated on Prevalence of left ventricular hypertrophy (LVMI >51 g/m^2.7) (p=<0.001). Children on chronic hemodialysis had a 60% prevalence of left ventricular hypertrophy, which was significantly higher than healthy controls, though it did not correlate significantly with blood pressure.
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