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February 1, 1994Archives of Disease in ChildhoodOpen Access

24 hour blood pressure monitoring in healthy and hypertensive children.

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Key result

24-hour ambulatory blood pressure monitoring established normal circadian BP values in healthy children (109/66 mmHg daytime, 96/52 mmHg nighttime) and detected disturbed rhythms in hypertensive cases.

Why the study?

Does 24-hour ABPM accurately measure daily blood pressure and detect circadian rhythm disturbances in healthy and hypertensive children?

Population

180 children, including 123 healthy schoolchildren, 24 with borderline or mild hypertension, 17 with renal…

Design

Cross-sectional

Follow-up

24 hours

Authors

GRGyörgy ReuszSemmelweis UniversityMHM HóborSemmelweis UniversityTTTivadar TulassaySemmelweis University

Discussion

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Implication

May inform pediatric ABPM interpretation; leaves open whether thresholds improve outcomes or guide therapy.

Key Points

  • To establish normal 24-hour ambulatory blood pressure values in healthy schoolchildren and assess blood pressure profiles in pediatric patients with hypertension or kidney disease.
  • Conducted 24-hour ambulatory blood pressure monitoring (ABPM) in 123 healthy children (mean age 12.5 years), 24 with borderline/mild hypertension, 17 with renal hypertension, 10 with chronic renal failure, and 6 with a renal allograft.
  • Validated monitor accuracy against a mercury column manometer across 60 comparisons and repeated ABPM in 8 children with renal disease following treatment modification.
  • Normal blood pressure for 123 healthy children averaged 109 (7)/66 (8) mmHg during daytime and 96 (8)/52 (7) mmHg during nighttime.
  • Elevated blood pressure was detected in 14 of 24 children with borderline/mild hypertension, and circadian rhythm was disturbed in 3 of 24 borderline cases, 4 of 17 with renal hypertension, and 5 of 16 with renal failure or transplant.
  • Monitor validation showed mean differences of -0.19 (1.75) mmHg systolic and -0.21 (2.11) mmHg diastolic, and all 8 re-evaluated renal patients had lower average blood pressure after treatment adjustment.

Study Design

Type

Cross-Sectional (n=180)

Structured PICO

Does 24-hour ABPM accurately measure daily blood pressure and detect circadian rhythm disturbances in healthy and hypertensive children?

P
Population
180 children, including 123 healthy schoolchildren and 57 with various forms of hypertension, evaluated using 24-hour ambulatory blood pressure monitoring.
E
Exposure
24-hour ambulatory blood pressure monitoring (ABPM)
O
Outcome
Daytime and nighttime blood pressure values and circadian rhythm patternssurrogate

24-hour ABPM is a reproducible and accurate method for establishing normal blood pressure values and detecting circadian rhythm disturbances in pediatric patients.

Cite This Study

Reusz et al. (1994) conducted a cross-sectional in Hypertension (n=180). 24-hour ambulatory blood pressure monitoring (ABPM) vs. Healthy controls was evaluated on Daytime and nighttime blood pressure and circadian rhythm disturbance. 24-hour ambulatory blood pressure monitoring established normal circadian BP values in healthy children (109/66 mmHg daytime, 96/52 mmHg nighttime) and detected disturbed rhythms in hypertensive cases.

synapsesocial.com/papers/6a9c69ac3a405cc3ac5d29fehttps://doi.org/10.1136/adc.70.2.90

Topics

Hypertension management
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Also Consider

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  1. 1Blood pressure during normal daily activities, sleep, and exercise. Comparison of values in normal and hypertensive subjects1982 · 532 citations
  2. 2Relationship Between Initial Cardiovascular Structural Changes and Daytime and Nighttime Blood Pressure Monitoring1992 · 171 citations
  3. 3Blood Pressure During Normal Daily Activities, Sleep, and Exercise1982 · 515 citations
  4. 4The Prognostic Value of Ambulatory Blood Pressures1983 · 856 citations
  5. 5Report of the Second Task Force on Blood Pressure Control in Children—19871987 · 1,149 citations