Key result
Brown adipose tissue from cold-acclimated rats retained relatively higher levels of respiration at temperatures below 20 °C compared to brown fat from control rats and liver tissue.
Population
Homogenates of brown fat and liver from control and cold-acclimated rats
Comparison
In vitro temperature variation over the range… vs Liver homogenates; control rats
Design
Preclinical
Authors
Loading...
Supports BAT thermogenic adaptation in rodents; leaves open translation to human physiology or therapies.
Brown adipose tissue from cold-acclimated rats shows decreased temperature sensitivity, supporting its adaptive role as a thermogenic effector.
Roberts et al. (1967) studied this question. Cold-acclimation and temperature variation (10-37 °C) vs. Control rats and liver tissue was evaluated on Metabolic rates (oxygen consumption) of homogenates. Brown adipose tissue from cold-acclimated rats retained relatively higher levels of respiration at temperatures below 20 °C compared to brown fat from control rats and liver tissue.