Key result
Levosimendan improved cardiac performance, symptomatic relief, and ventricular function in a woman with post-partum cardiomyopathy.
Why the study?
Does levosimendan improve cardiac function and symptoms in patients with post-partum cardiomyopathy?
Case Report (n=1)
Does levosimendan improve cardiac function and symptoms in patients with post-partum cardiomyopathy?
This case report suggests levosimendan may be an effective initial therapy for acute heart failure secondary to post-partum cardiomyopathy.
Supports further investigation of levosimendan in peripartum cardiomyopathy; should not change practice based on single case report.
OBJECTIVE: To describe the use of levosimendan, a novel inotropic agent, for the treatment of post-partum cardiomyopathy (PPCMO). METHODS: The authors present the second recorded use of levosimendan for a woman with PPCMO. RESULTS: Levosimendan improved cardiac performance which was associated with symptomatic relief and echocardiographic improvement in ventricular function. The patient recovered from this episode of acute cardiac failure and continues to show steady improvement in cardiac function. CONCLUSIONS: Levosimendan proved a useful agent when used as initial therapy in this case of PPCMO.
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Nguyen et al. (2005) conducted a case report in Post-partum cardiomyopathy (PPCMO) (n=1). Levosimendan was evaluated on Cardiac performance and ventricular function. Levosimendan improved cardiac performance, symptomatic relief, and ventricular function in a woman with post-partum cardiomyopathy.
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