Key result
Progesterone successfully induced verapamil-sensitive idiopathic left ventricular tachycardia post-pregnancy, allowing for successful radiofrequency ablation.
Case Report (n=1)
This is the first reported case demonstrating that pregnancy-associated idiopathic ventricular tachycardia can be induced post-pregnancy by recreating the hormonal milieu with progesterone to facilitate ablation.
May enable ablation of select post-pregnancy ILVT; single-case report leaves broader adoption open.
Successful Induction With Progesterone and Radiofrequency Ablation. Verapamil-sensitive idiopathic left ventricular tachycardia in pregnancy is a rare diagnosis. We report a case of a primigravida female with new onset fascicular ventricular tachycardia that was managed with oral verapamil. Post pregnancy, the tachycardia was not inducible in the electrophysioplogy lab. Progesterone, a hormone associated with pregnant state, was used to successfully induce the tachycardia, which was ablated. This is the first reported case of an idiopathic ventricular tachycardia associated with pregnancy that could be induced later by recreating the hormonal milieu associated with pregnant state.
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Makhija et al. (2010) conducted a case report in Verapamil-sensitive idiopathic left ventricular tachycardia (n=1). Progesterone and radiofrequency ablation was evaluated on Induction of tachycardia. Progesterone successfully induced verapamil-sensitive idiopathic left ventricular tachycardia post-pregnancy, allowing for successful radiofrequency ablation.
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