Key result
In patients with mitral stenosis, Aschoff lesions were found in 40% of left auricular appendages, with a significant decrease in their presence when thrombosis was present.
Observational (n=183)
Aschoff bodies are present in 40% of left auricular appendages removed during mitral stenosis surgery, and their presence is inversely correlated with thrombosis.
May indicate active rheumatic carditis in mitral stenosis; leaves open thrombosis link and clinical relevance.
Left auricular appendages from 183 patients, removed at operation for mitral stenosis, have been studied with regard to presence of Aschoff bodies and endocardial thrombi. An over-all incidence of Aschoff lesions of 40 per cent was found. There was a significant decrease in Aschoff lesions in the presence of thrombosis. The occurrence of Aschoff bodies in the appendages is correlated with the findings in the remainder of the heart in autopsied cases.
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Decker et al. (1953) conducted an observational in Mitral stenosis (n=183). Presence of endocardial thrombi vs. Absence of endocardial thrombi was evaluated on Presence of Aschoff bodies. In patients with mitral stenosis, Aschoff lesions were found in 40% of left auricular appendages, with a significant decrease in their presence when thrombosis was present.
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