Key result
Current was a more accurate parameter than energy for dose response assessment of transthoracic defibrillation, with 90% of successful trials occurring at or above 0.85 DFT and 0.55 DFT, respectively.
Why the study?
Does a current-based model provide a more accurate dose response assessment of transthoracic defibrillation compared to an energy-based model in a canine model?
Population
Pentobarbital anesthetized dogs (n = 8) undergoing ventricular fibrillation induction
Comparison
Current-based dose response assessment of… vs Energy-based dose response assessment of…
Design
Preclinical, Three shocks were delivered in random order at each of seven…
Authors
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Current may enhance transthoracic defibrillation dosing accuracy; leaves open human validation from this canine model.
RCT (n=8)
Random order
Does a current-based model provide a more accurate dose response assessment of transthoracic defibrillation compared to an energy-based model in a canine model?
Current is a more accurate parameter than energy in the dose response assessment of transthoracic defibrillation in a canine model.
Wesley et al. (1991) conducted an RCT in Ventricular fibrillation (n=8). Current-based defibrillation vs. Energy-based defibrillation was evaluated on Percent successful defibrillation. Current was a more accurate parameter than energy for dose response assessment of transthoracic defibrillation, with 90% of successful trials occurring at or above 0.85 DFT and 0.55 DFT, respectively.
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