Key result
Peak current was correlated with energy requirements after correcting for heart weight (r=0.76, P<0.01), suggesting current per unit heart weight is a better descriptor for defibrillation ability.
Why the study?
Does peak current or energy better describe the ability to defibrillate in a canine model?
Population
18 dogs subjected to repeated fibrillation-defibrillation
Design
Preclinical
Authors
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May guide preclinical defibrillation research toward current-based metrics; leaves open translation to clinical practice.
Does peak current or energy better describe the ability to defibrillate in a canine model?
Effect estimate: r = 0.76
p-value: p=<0.01
Current per unit heart weight may be a more consistent descriptor for defibrillation efficacy than energy.
DORIAN et al. (1988) studied Cardiac fibrillation (n=18). Defibrillation shocks was evaluated on Energy and current requirements for defibrillation (r = 0.76, p=<0.01). Peak current was correlated with energy requirements after correcting for heart weight (r=0.76, P<0.01), suggesting current per unit heart weight is a better descriptor for defibrillation ability.
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