Key result
Inhaled sodium cromoglycate (20 mg, 4 times daily) suppressed ACE inhibitor-induced cough in 3 out of 5 patients.
Why the study?
Does inhaled sodium cromoglycate suppress cough in patients with ACE inhibitor-induced cough?
Case Report (n=5)
Does inhaled sodium cromoglycate suppress cough in patients with ACE inhibitor-induced cough?
Answers are grounded in this paper and cite their sources.
Inhaled sodium cromoglycate may suppress ACE inhibitor-induced cough in a subset of patients, potentially offering an alternative to drug withdrawal.
The beneficial effects of angiotensin converting enzyme (ACE) inhibitors may be limited by cough, for which the only consistently effective treatment is withdrawal of therapy. The effect of inhaled sodium cromoglycate (20 mg, 4 times daily) was examined in five patients who experienced cough following the introduction of an ACE inhibitor. In three patients inhaled cromoglycate suppressed the cough. Inhaled sodium cromoglycate may thus be of value in a proportion of patients with ACE inhibitor-induced cough.
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Mark Hargreaves (1993) conducted a case report in ACE inhibitor-induced cough (n=5). Inhaled sodium cromoglycate was evaluated on Suppression of cough. Inhaled sodium cromoglycate (20 mg, 4 times daily) suppressed ACE inhibitor-induced cough in 3 out of 5 patients.
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