Key result
Thrombomodulin was expressed in the syncytiotrophoblast of hydatidiform mole and uterine choriocarcinoma, but not in gastric choriocarcinoma, whereas hCG was present in all three.
Population
Tissue samples of chorionic diseases of the uterus and choriocarcinomas of the stomach
Design
Other
Authors
Loading...
May aid histologic distinction of uterine from gastric choriocarcinoma; leaves open diagnostic validation in larger cohorts.
Observational
Thrombomodulin expression differentiates uterine from gastric choriocarcinoma, unlike hCG which is present in both.
Yonezawa et al. (1988) conducted an observational in Chorionic diseases of the uterus and choriocarcinoma of the stomach. Thrombomodulin (TM) expression was evaluated on Presence of TM and hCG in syncytiotrophoblastic cells. Thrombomodulin was expressed in the syncytiotrophoblast of hydatidiform mole and uterine choriocarcinoma, but not in gastric choriocarcinoma, whereas hCG was present in all three.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: