Key result
A 59-year-old male presenting with dyspnea and hemoptysis was diagnosed with metastatic angiosarcoma, highlighting this rare malignancy as a potential cause of diffuse pulmonary hemorrhage.
Case Report (n=1)
Metastatic angiosarcoma should be considered as a rare cause of hemoptysis and diffuse pulmonary hemorrhage.
Metastatic angiosarcoma warrants consideration in unexplained pulmonary hemorrhage; leaves open its prevalence and diagnostic yield pending larger studies.
Angiosarcomas are rare, malignant, endothelial-cell tumors of vascular origin that can arise at any body site. They frequently metastasize to the lung, heralded by dyspnea, hemoptysis, chest pain, pneumothoraces, and diffuse pulmonary hemorrhage. However, in most cases lung metastases are discovered after the diagnosis of a primary angiosarcoma has already been established. Very rarely will an undiagnosed metastatic angiosarcoma present as diffuse pulmonary hemorrhage. We describe the case of a 59-year-old male who presented to hospital with dyspnea and hemoptysis. CT chest revealed rapidly progressing nodular changes and broncho-alveolar lavage returns were progressively bloody. Open lung wedge biopsy ultimately revealed metastatic angiosarcoma and extensive pulmonary hemorrhage. Our case highlights the key clinical, radiological, and pathological features of this rare malignancy that frequently metastasizes to the lung and reminds clinicians to consider it as a cause of hemoptysis and pulmonary hemorrhage.
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Aversa et al. (2014) conducted a case report in Metastatic angiosarcoma presenting as hemoptysis and pulmonary hemorrhage (n=1). A 59-year-old male presenting with dyspnea and hemoptysis was diagnosed with metastatic angiosarcoma, highlighting this rare malignancy as a potential cause of diffuse pulmonary hemorrhage.
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