Key result
Metastatic angiosarcoma can present as diffuse pulmonary hemorrhage, as seen in 7 patients whose biopsies all showed hemorrhage associated with atypical epithelioid and spindle cells.
Case Report (n=7)
Angiosarcoma should be considered in the differential diagnosis of diffuse pulmonary hemorrhage, particularly in young adults, as it can be a presenting manifestation of metastatic disease, including primary cardiac tumors.
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Angiosarcoma merits inclusion in the differential for diffuse pulmonary hemorrhage; this case series extends recognized metastatic presentations but remains hypothesis-generating.
Adem et al. (2001) conducted a case report in Metastatic angiosarcoma presenting with diffuse pulmonary hemorrhage (n=7). Metastatic angiosarcoma was evaluated on Clinical, radiologic, and pathologic findings. Metastatic angiosarcoma can present as diffuse pulmonary hemorrhage, as seen in 7 patients whose biopsies all showed hemorrhage associated with atypical epithelioid and spindle cells.
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