Key result
Higher carotid intima media thickness predicted cardiovascular events in Chinese predialysis CKD patients, with each higher IMT quartile conferring a 41.6% excess hazard (95% CI 6.4-88.4%; P=0.017).
Why the study?
Does carotid IMT predict cardiovascular events in Chinese predialysis patients with stages 3 to 4 CKD?
Population
203 Chinese predialysis patients with stages 3 to 4 chronic kidney disease (CKD)
Comparison
Carotid intima media thickness measurement by… vs Lower quartiles of carotid IMT
Design
Cohort
Follow-up
48 months
Authors
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May aid CV risk stratification in Chinese predialysis CKD; leaves open prospective validation before routine use.
Cohort (n=203)
Does carotid IMT predict cardiovascular events in Chinese predialysis patients with stages 3 to 4 CKD?
Hazard Ratio: 1.416 (95% CI 1.064–1.884)
p-value: p=0.017
Carotid IMT is a strong predictor of cardiovascular events in predialysis patients with stages 3 to 4 CKD, suggesting its utility for risk stratification.
Szeto et al. (2007) conducted a cohort in Stages 3 to 4 chronic kidney disease (n=203). Carotid intima media thickness vs. Lower IMT quartiles was evaluated on Cardiovascular event (Excess hazard 41.6%, 95% CI 6.4-88.4%, p=0.017). Higher carotid intima media thickness predicted cardiovascular events in Chinese predialysis CKD patients, with each higher IMT quartile conferring a 41.6% excess hazard (95% CI 6.4-88.4%; P=0.017).
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