Key result
Obesity-related disease profiles correlated with lower adiponectin levels independently of age, sex, BMI, and HOMA-IR, particularly in type 2 diabetic and hypertensive groups.
Observational (n=400)
Hypoadiponectinaemia is independently associated with obesity-related disease profiles, suggesting a role in the development of obesity complications.
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Hypoadiponectinemia was associated with obesity complications in diabetes and hypertension; leaves open causal role and need for prospective trials before clinical adoption.
Ebinç et al. (2008) conducted an observational in Obesity-related diseases (n=400). Obesity-related disease profiles vs. Lean subjects (BMI < 25 kg/m2) was evaluated on HOMA-IR index and adiponectin levels. Obesity-related disease profiles correlated with lower adiponectin levels independently of age, sex, BMI, and HOMA-IR, particularly in type 2 diabetic and hypertensive groups.
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