Key result
Young adults with family origin in eastern Finland had significantly greater carotid IMT (0.592 vs 0.565 mm; P<0.0001) and lower brachial FMD than western Finns.
Why the study?
Does geographic family origin from eastern Finland increase carotid IMT and decrease brachial FMD in young Finnish adults?
Population
2264 white adults, aged 24 to 39 years, from Finland
Comparison
Geographic family origin in eastern Finland vs Geographic family origin in western Finland
Design
Cohort
Authors
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Eastern Finnish family origin was associated with higher subclinical atherosclerosis; leaves open genetic versus environmental drivers of regional CV disparities.
Cohort (n=2,264)
Does geographic family origin from eastern Finland increase carotid IMT and decrease brachial FMD in young Finnish adults?
Absolute Event Rate: 0.592% vs 0.565%
p-value: p=<0.0001
Young adults with family origins in eastern Finland have greater subclinical atherosclerosis markers than those from western Finland, suggesting a heritable component to regional cardiovascular risk differences.
Juonala et al. (2004) conducted a cohort in Subclinical atherosclerosis (n=2,264). Family origin in eastern Finland vs. Family origin in western Finland was evaluated on Carotid intima-media thickness (IMT) (p=<0.0001). Young adults with family origin in eastern Finland had significantly greater carotid IMT (0.592 vs 0.565 mm; P<0.0001) and lower brachial FMD than western Finns.
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