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June 26, 2020Catheterization and Cardiovascular Interventions

Outcomes of urgent/emergent transcatheter mitral valve repair ( MitraClip ): A single center experience

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Key result

Urgent/emergent transcatheter mitral valve repair in high-risk patients with heart failure or cardiogenic shock resulted in 21% 30-day mortality and 50% mortality over a median 153 days.

Why the study?

TMVr is used for select patients with severe mitral regurgitation, but knowledge regarding outcomes for urgent/emergent TMVr is limited.

Population

20 patients undergoing urgent/emergent TMVr using MitraClip

Comparison

Survivors vs nonsurvivors

Design

Single-center retrospective chart review

Follow-up

Median 153 days (IQR 20-491)

Authors

CKChristopher P. KovachUniversity of Colorado Anschutz Medical CampusSBSean BellUniversity of Nebraska at OmahaAKAkash KatarukaUniversity of Washington

Discussion

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Member takes

Overview

Urgent/emergent TMVr was associated with high short-term mortality in shock or decompensated HF; leaves open optimal selection and periprocedural management for prospective trials.

Study Design

Type

Observational (n=20)

Multicenter

No

Structured PICO

P
Population
20 high-risk patients with acute decompensated heart failure or cardiogenic shock who underwent urgent/emergent transcatheter mitral valve repair, followed for a median of 153 days.
E
Exposure
Urgent/emergent transcatheter edge-to-edge mitral valve repair (TMVr) using MitraClip
O
Outcome
All-cause mortality, hospital mortality, procedural success, periprocedural complications, and hospital readmissionhard clinical

Urgent/emergent TMVr in high-risk patients with ADHF or cardiogenic shock is associated with high short-term mortality and periprocedural complications, highlighting the need for careful patient selection.

Limitations

  • Single-center retrospective analysis
  • single-center
  • retrospective analysis

Cite This Study

Kovach et al. (2020) conducted an observational in Severe mitral regurgitation with acute decompensated heart failure or cardiogenic shock (n=20). Urgent/emergent transcatheter edge-to-edge mitral valve repair (TMVr) was evaluated on 30-day mortality. Urgent/emergent transcatheter mitral valve repair in high-risk patients with heart failure or cardiogenic shock resulted in 21% 30-day mortality and 50% mortality over a median 153 days.

synapsesocial.com/papers/6a9d0033e1f32669ee55ff62https://doi.org/10.1002/ccd.29084

Topics

Mitral valve intervention
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Early Revascularization in Acute Myocardial Infarction Complicated by Cardiogenic Shock1999 · 3,149 citations
  2. 2Percutaneous Mitral Valve Interventions in the Real World2013 · 840 citations
  3. 3MitraClip Therapy in Critically Ill Patients with Severe Functional Mitral Regurgitation and Refractory Heart Failure2019 · 11 citations
  4. 4Refining the prognostic impact of functional mitral regurgitation in chronic heart failure2017 · 359 citations