Key result
Patients with acute myocardial infarction and culprit left main coronary artery stenosis had significantly higher in-hospital mortality compared to those with non-culprit stenosis (16.0% vs 8.9%).
Why the study?
Does PCI with DES yield comparable clinical outcomes to CABG in patients with acute MI and unprotected LMCA stenosis?
Cohort (n=587)
Yes
Does PCI with DES yield comparable clinical outcomes to CABG in patients with acute MI and unprotected LMCA stenosis?
Absolute Event Rate: 16% vs 8.9%
p-value: p=0.008
In patients with acute MI and unprotected LMCA stenosis, culprit LMCA is associated with higher in-hospital mortality than non-culprit LMCA, while PCI with DES demonstrates similar early and 12-month outcomes compared to CABG.
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Culprit left main stenosis in acute MI was associated with higher in-hospital mortality; leaves open optimal revascularization strategy in this high-risk subgroup.
Sim et al. (2013) conducted a cohort in Acute myocardial infarction with unprotected left main coronary artery stenosis (n=587). Culprit left main coronary artery (LMCA) stenosis vs. Non-culprit LMCA stenosis was evaluated on In-hospital mortality (p=0.008). Patients with acute myocardial infarction and culprit left main coronary artery stenosis had significantly higher in-hospital mortality compared to those with non-culprit stenosis (16.0% vs 8.9%).
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