Why the study?
Does adjuvant chemotherapy using vincristine, cyclophosphamide, and adriamycin improve disease-free survival in patients with localized Ewing's sarcoma compared to historical controls?
Population
28 patients with localized Ewing's sarcoma
Comparison
Adjuvant chemotherapy using vincristine… vs Historical control
Design
Cohort
Follow-up
3 years
Authors
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May support adjuvant chemotherapy in localized Ewing's sarcoma; leaves open confirmation in randomized trials.
Does adjuvant chemotherapy using vincristine, cyclophosphamide, and adriamycin improve disease-free survival in patients with localized Ewing's sarcoma compared to historical controls?
Adjuvant chemotherapy with vincristine, cyclophosphamide, and adriamycin significantly improves disease-free survival in localized Ewing's sarcoma.
Advani et al. (1986) studied this question.
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