Key result
Increased liver stiffness was associated with a higher risk of adverse cardiac events in patients hospitalized with acute decompensated heart failure (HR 1.15; 95% CI 1.04-1.28; p=0.006).
Why the study?
Does increased liver stiffness predict adverse cardiac events in patients hospitalized with acute decompensated heart failure?
Meta-Analysis (n=792)
Does increased liver stiffness predict adverse cardiac events in patients hospitalized with acute decompensated heart failure?
Hazard Ratio: 1.15 (95% CI 1.04–1.28)
p-value: p=0.006
Increased liver stiffness, assessed non-invasively, is a significant independent prognostic marker for adverse cardiovascular outcomes in patients hospitalized with acute decompensated heart failure.
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May improve post-discharge risk stratification in ADHF; leaves open whether routine integration enhances outcomes or changes practice.
Khan et al. (2018) conducted a meta-analysis in Acute decompensated heart failure (n=792). Increased liver stiffness vs. Normal/lower liver stiffness was evaluated on Adverse cardiac events (cardiac death or repeat heart failure hospitalization) (HR 1.15, 95% CI 1.04-1.28, p=0.006). Increased liver stiffness was associated with a higher risk of adverse cardiac events in patients hospitalized with acute decompensated heart failure (HR 1.15; 95% CI 1.04-1.28; p=0.006).