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October 3, 2018BMJ Case Reports4 citationsOpen Access

Heart of the matter: reverse takotsubo syndrome in an anthracycline-exposed oncology patient

JVJay VoitATAnjan TibrewalaNANausheen Akhter

Key Result

Two-dimensional speckle-tracking echocardiography derived strain helped diagnose reverse takotsubo syndrome in a 24-year-old man with anthracycline exposure and acute heart failure.

Study Design

Type

Case Report (n=1)

Structured PICO

P
Population
A 24-year-old man with acute myelogenous leukaemia and a history of anthracycline treatment who developed new-onset heart failure diagnosed as reverse takotsubo syndrome.
E
Exposure
Two-dimensional speckle-tracking echocardiography (2DSTE) derived strain imaging
O
Outcome
Diagnosis of reverse takotsubo syndrome

Two-dimensional speckle-tracking echocardiography derived strain can help differentiate reverse takotsubo syndrome from anthracycline-induced cardiotoxicity in oncology patients presenting with acute heart failure.

Abstract

A 24-year-old man with acute myelogenous leukaemia and a history of anthracycline treatment is hospitalised for non-anthracycline chemotherapy. He develops new-onset heart failure requiring intesive care unit (ICU) admission during his stay. There is debate as to the aetiology of his heart failure, whether anthracycline cardiotoxicity or takotsubo syndrome. He is diuresed and discharged home with close follow-up. Ultimately, the retrospective use of two-dimensional speckle-tracking echocardiography derived strain helps diagnose reverse takotsubo syndrome.

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Cite This Study

Voit et al. (2018) conducted a case report in Reverse takotsubo syndrome, acute myelogenous leukaemia, heart failure (n=1). Anthracycline chemotherapy was evaluated. Two-dimensional speckle-tracking echocardiography derived strain helped diagnose reverse takotsubo syndrome in a 24-year-old man with anthracycline exposure and acute heart failure.

synapsesocial.com/papers/6a9d43471f124ec13ed9a7echttps://doi.org/10.1136/bcr-2018-226378
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