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December 1, 1991Journal of Cardiac Surgery

The Cryopreserved Homograft Valve in the Pulmonary Position: Mid-Term Results and Technical Considerations

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Key result

Cryopreserved homograft valves implanted in the pulmonary position demonstrated good mid-term function with an operative mortality of 3.3% (2/56) and 51 long-term survivors.

Population

56 patients undergoing implantation of a valve in the pulmonary position.

Design

Case_series

Follow-up

1 month to 5 1/2 years

Authors

JLJohn J. LambertiLucile Packard Children's HospitalLGLily GeorgeBoston Children's HospitalJMJames W. MathewsonSt. Joseph's Hospital and Medical Center

Discussion

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Overview

May inform conduit selection in congenital surgery; hypothesis-generating and should not yet change practice.

Study Design

Type

Observational (n=56)

Structured PICO

P
Population
56 patients aged 15 days to 22 years who underwent implantation of cryopreserved homograft valves in the pulmonary position, followed for 1 month to 5.5 years.
E
Exposure
Implantation of cryopreserved homograft valves (12 aortic and 48 pulmonary) in the pulmonary position.
O
Outcome
Operative mortality, late deaths, homograft replacement, and clinical/functional status (including pulmonary insufficiency murmurs) at mid-term follow-up.hard clinical

Cryopreserved homograft valves function well in the right ventricular outflow tract with low operative mortality and good mid-term clinical outcomes in pediatric and young adult patients.

Limitations

  • Longer term follow-up is necessary to confirm the superiority of the cryopreserved homograft when compared to the porcine heterograft in the right ventricular outflow tract.

Cite This Study

Lamberti et al. (1991) reported an observational. Cryopreserved homograft valves in the pulmonary position was evaluated on Operative mortality. Cryopreserved homograft valves implanted in the pulmonary position demonstrated good mid-term function with an operative mortality of 3.3% (2/56) and 51 long-term survivors.

synapsesocial.com/papers/6a9d44df894d4c85b98b04dbhttps://doi.org/10.1111/jocs.1991.6.4s.627
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Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Pulmonary Valve Autotransplantation (The Ross Operation)1988 · 50 citations
  2. 2T. Duckett Jones Memorial Lecture. The Jones criteria and the challenges of clinimetrics.1982 · 222 citations