Key result
Pregnancy induced a significant increase in muscle sympathetic nerve activity in women at risk for preeclampsia compared to postpartum values (29 vs 9 bursts/min; P<0.05).
Cohort (n=22)
p-value: p=<0.05
Pregnancy induces sympathetic overactivity in women at risk for preeclampsia, but this overactivity alone does not differentiate those who will subsequently develop preeclampsia from those who will remain normotensive.
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Does not differentiate preeclampsia developers among at-risk women; leaves open sympathetic role in pathogenesis.
Fischer et al. (2004) conducted a cohort in Increased risk for preeclampsia (n=22). Pregnancy vs. Postpartum state was evaluated on Muscle sympathetic nerve activity (MSNA) (p=<0.05). Pregnancy induced a significant increase in muscle sympathetic nerve activity in women at risk for preeclampsia compared to postpartum values (29 vs 9 bursts/min; P<0.05).
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