Key result
Dobutamine infusion in children after cardiopulmonary bypass increased cardiac index but caused significant tachycardia, necessitating discontinuation in 4 of 11 subjects.
Why the study?
Does dobutamine infusion improve hemodynamics without unacceptable side effects in children after cardiopulmonary bypass?
Population
11 children after surgical correction of congenital heart disease (after cardiopulmonary bypass)
Comparison
Dobutamine infusion at 1, 4, 7, and 10… vs Baseline/control
Design
Case_series
Authors
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Dobutamine may raise cardiac index yet trigger limiting tachycardia in children after bypass; leaves open net benefit and requires prospective trials.
Does dobutamine infusion improve hemodynamics without unacceptable side effects in children after cardiopulmonary bypass?
Dobutamine increases cardiac index in children after cardiopulmonary bypass but causes significant tachycardia, potentially making it unsuitable for this population.
Bohn et al. (1980) studied Congenital heart disease after surgical correction (n=11). Dobutamine vs. Baseline (control) was evaluated on Cardiac index and heart rate. Dobutamine infusion in children after cardiopulmonary bypass increased cardiac index but caused significant tachycardia, necessitating discontinuation in 4 of 11 subjects.
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