Why the study?
Less is known about physiological characteristics such as arterial stiffness in old-old adults (aged ≥75 years), particularly those aged >85 years.
Population
559 Japanese community dwellers aged >65 y in Osaka and Kawakami Village, Nara
Comparison
Old-old (age ≥75 y) vs young-old (age 65-74 y) adults
Design
Cross-sectional observational study
Key result
Advancing age was significantly associated with increased blood pressure and arterial stiffness and decreased physical fitness, although nonagenarians maintained relatively lower arterial stiffness.
Authors
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Supports monitoring vascular health with age; leaves open whether preserved stiffness in nonagenarians reflects selection or modifiable factors.
Cross-Sectional (n=559)
Yes
p-value: p=<0.001
Arterial stiffness and blood pressure increase with advancing age in older adults, but nonagenarians may maintain longevity characteristics of lower arterial stiffness and higher physical fitness.
Nishiwaki et al. (2019) conducted a cross-sectional in Aging (n=559). Advancing age vs. Younger age groups (e.g., 65-74 years) was evaluated on Trends in blood pressure, arterial stiffness, and physical fitness with advancing age (p=<0.001). Advancing age was significantly associated with increased blood pressure and arterial stiffness and decreased physical fitness, although nonagenarians maintained relatively lower arterial stiffness.
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